Antiviral therapy in management of COVID-19: a systematic review on current evidence
Identifieur interne : 000294 ( Main/Exploration ); précédent : 000293; suivant : 000295Antiviral therapy in management of COVID-19: a systematic review on current evidence
Auteurs : Mahmoud Yousefifard [Iran] ; Alireza Zali [Iran] ; Kosar Mohamed Ali [Iraq] ; Arian Madani Neishaboori [Iran] ; Afshin Zarghi [Iran] ; Mostafa Hosseini [Iran] ; Saeed Safari [Iran]Source :
- Archives of Academic Emergency Medicine [ 2645-4904 ] ; 2020.
Abstract
The purpose of the current systematic review is to evaluate the efficacy of antiviral therapies in treatment of COVID-19. In addition, clinical trials on the efficacy of antiviral therapies in the management of Severe Acute Respiratory Syndrome coronavirus (SARS-Cov) or Middle East Respiratory Syndrome coronavirus (MERS-CoV) have also been reviewed, in order to identify potential treatment options for COVID-19.
An extensive search was performed in Medline, Embase, Scopus, Web of Science and CENTRAL databases until the end of March 15, 2020. Two independent researchers performed the screening, and finally the related studies were included.
Only one clinical trial on the efficacy of antiviral therapy in management of COVID-19 was found. The results depicted that adding Lopinavir-Ritonavir to the standard treatment regimen of patients with severe COVID-19 has no benefits. Moreover, 21 case-series and case-report studies reported the prescription of antiviral agents in COVID-19, none of which can be used to determine the efficacy of antiviral therapies in confronting COVID-19. In addition, no clinical trials were found to be performed on the efficacy of antiviral agents in the management of SARS-CoV and MERS-CoV.
The current evidence impede researchers from proposing an appropriate antiviral therapy against COVID-19, making the current situation a serious concern for international organizations such as World Health Organization (WHO). In the time of the current pandemic and future epidemics, organizations such as WHO should pursue more proactive actions and plan well-designed clinical trials so that their results can be used in managing future epidemics.
Url:
PubMed: NONE
PubMed Central: 7156260
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 001291
- to stream Pmc, to step Curation: 001291
- to stream Pmc, to step Checkpoint: 000120
- to stream Ncbi, to step Merge: 002B79
- to stream Ncbi, to step Curation: 002B79
- to stream Ncbi, to step Checkpoint: 002B79
- to stream Main, to step Merge: 000297
- to stream Main, to step Curation: 000294
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Antiviral therapy in management of COVID-19: a systematic review on current evidence</title><author><name sortKey="Yousefifard, Mahmoud" sort="Yousefifard, Mahmoud" uniqKey="Yousefifard M" first="Mahmoud" last="Yousefifard">Mahmoud Yousefifard</name><affiliation wicri:level="1"><nlm:aff id="aff1">Physiology Research Center, Iran University of Medical Sciences, Tehran, Iran.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Iran</country><wicri:regionArea>Physiology Research Center, Iran University of Medical Sciences, Tehran</wicri:regionArea><wicri:noRegion>Tehran</wicri:noRegion></affiliation></author><author><name sortKey="Zali, Alireza" sort="Zali, Alireza" uniqKey="Zali A" first="Alireza" last="Zali">Alireza Zali</name><affiliation wicri:level="1"><nlm:aff id="aff2">Functional Neurosurgery Research Center, Shohada Tajrish Neurosurgical Comprehensive Center of Excellence, Shahid Beheshti University of Medical Sciences, Tehran, Iran.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Iran</country><wicri:regionArea>Functional Neurosurgery Research Center, Shohada Tajrish Neurosurgical Comprehensive Center of Excellence, Shahid Beheshti University of Medical Sciences, Tehran</wicri:regionArea><wicri:noRegion>Tehran</wicri:noRegion></affiliation></author><author><name sortKey="Mohamed Ali, Kosar" sort="Mohamed Ali, Kosar" uniqKey="Mohamed Ali K" first="Kosar" last="Mohamed Ali">Kosar Mohamed Ali</name><affiliation wicri:level="1"><nlm:aff id="aff3">College of medicine, University of Sulaimani, Sulaimani, Iraq.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Iraq</country><wicri:regionArea>College of medicine, University of Sulaimani, Sulaimani</wicri:regionArea><wicri:noRegion>Sulaimani</wicri:noRegion></affiliation></author><author><name sortKey="Madani Neishaboori, Arian" sort="Madani Neishaboori, Arian" uniqKey="Madani Neishaboori A" first="Arian" last="Madani Neishaboori">Arian Madani Neishaboori</name><affiliation wicri:level="1"><nlm:aff id="aff1">Physiology Research Center, Iran University of Medical Sciences, Tehran, Iran.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Iran</country><wicri:regionArea>Physiology Research Center, Iran University of Medical Sciences, Tehran</wicri:regionArea><wicri:noRegion>Tehran</wicri:noRegion></affiliation></author><author><name sortKey="Zarghi, Afshin" sort="Zarghi, Afshin" uniqKey="Zarghi A" first="Afshin" last="Zarghi">Afshin Zarghi</name><affiliation wicri:level="1"><nlm:aff id="aff4">Department of Medicinal Chemistry, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Iran</country><wicri:regionArea>Department of Medicinal Chemistry, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran</wicri:regionArea><wicri:noRegion>Tehran</wicri:noRegion></affiliation></author><author><name sortKey="Hosseini, Mostafa" sort="Hosseini, Mostafa" uniqKey="Hosseini M" first="Mostafa" last="Hosseini">Mostafa Hosseini</name><affiliation><nlm:aff id="aff5">Pediatric Chronic Kidney Disease Research Center, Tehran University of Medical Sciences, Tehran Iran.</nlm:aff><wicri:noCountry code="subfield">Tehran Iran.</wicri:noCountry></affiliation><affiliation wicri:level="1"><nlm:aff id="aff6">Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Iran</country><wicri:regionArea>Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran</wicri:regionArea><wicri:noRegion>Tehran</wicri:noRegion></affiliation></author><author><name sortKey="Safari, Saeed" sort="Safari, Saeed" uniqKey="Safari S" first="Saeed" last="Safari">Saeed Safari</name><affiliation wicri:level="1"><nlm:aff id="aff7">Proteomics Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Iran</country><wicri:regionArea>Proteomics Research Center, Shahid Beheshti University of Medical Sciences, Tehran</wicri:regionArea><wicri:noRegion>Tehran</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff8">Emergency Department, Shohadye Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Iran</country><wicri:regionArea>Emergency Department, Shohadye Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran</wicri:regionArea><wicri:noRegion>Tehran</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmc">7156260</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156260</idno><idno type="RBID">PMC:7156260</idno><idno type="pmid">NONE</idno><date when="2020">2020</date><idno type="wicri:Area/Pmc/Corpus">001291</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001291</idno><idno type="wicri:Area/Pmc/Curation">001291</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">001291</idno><idno type="wicri:Area/Pmc/Checkpoint">000120</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000120</idno><idno type="wicri:Area/Ncbi/Merge">002B79</idno><idno type="wicri:Area/Ncbi/Curation">002B79</idno><idno type="wicri:Area/Ncbi/Checkpoint">002B79</idno><idno type="wicri:Area/Main/Merge">000297</idno><idno type="wicri:Area/Main/Curation">000294</idno><idno type="wicri:Area/Main/Exploration">000294</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Antiviral therapy in management of COVID-19: a systematic review on current evidence</title><author><name sortKey="Yousefifard, Mahmoud" sort="Yousefifard, Mahmoud" uniqKey="Yousefifard M" first="Mahmoud" last="Yousefifard">Mahmoud Yousefifard</name><affiliation wicri:level="1"><nlm:aff id="aff1">Physiology Research Center, Iran University of Medical Sciences, Tehran, Iran.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Iran</country><wicri:regionArea>Physiology Research Center, Iran University of Medical Sciences, Tehran</wicri:regionArea><wicri:noRegion>Tehran</wicri:noRegion></affiliation></author><author><name sortKey="Zali, Alireza" sort="Zali, Alireza" uniqKey="Zali A" first="Alireza" last="Zali">Alireza Zali</name><affiliation wicri:level="1"><nlm:aff id="aff2">Functional Neurosurgery Research Center, Shohada Tajrish Neurosurgical Comprehensive Center of Excellence, Shahid Beheshti University of Medical Sciences, Tehran, Iran.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Iran</country><wicri:regionArea>Functional Neurosurgery Research Center, Shohada Tajrish Neurosurgical Comprehensive Center of Excellence, Shahid Beheshti University of Medical Sciences, Tehran</wicri:regionArea><wicri:noRegion>Tehran</wicri:noRegion></affiliation></author><author><name sortKey="Mohamed Ali, Kosar" sort="Mohamed Ali, Kosar" uniqKey="Mohamed Ali K" first="Kosar" last="Mohamed Ali">Kosar Mohamed Ali</name><affiliation wicri:level="1"><nlm:aff id="aff3">College of medicine, University of Sulaimani, Sulaimani, Iraq.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Iraq</country><wicri:regionArea>College of medicine, University of Sulaimani, Sulaimani</wicri:regionArea><wicri:noRegion>Sulaimani</wicri:noRegion></affiliation></author><author><name sortKey="Madani Neishaboori, Arian" sort="Madani Neishaboori, Arian" uniqKey="Madani Neishaboori A" first="Arian" last="Madani Neishaboori">Arian Madani Neishaboori</name><affiliation wicri:level="1"><nlm:aff id="aff1">Physiology Research Center, Iran University of Medical Sciences, Tehran, Iran.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Iran</country><wicri:regionArea>Physiology Research Center, Iran University of Medical Sciences, Tehran</wicri:regionArea><wicri:noRegion>Tehran</wicri:noRegion></affiliation></author><author><name sortKey="Zarghi, Afshin" sort="Zarghi, Afshin" uniqKey="Zarghi A" first="Afshin" last="Zarghi">Afshin Zarghi</name><affiliation wicri:level="1"><nlm:aff id="aff4">Department of Medicinal Chemistry, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Iran</country><wicri:regionArea>Department of Medicinal Chemistry, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran</wicri:regionArea><wicri:noRegion>Tehran</wicri:noRegion></affiliation></author><author><name sortKey="Hosseini, Mostafa" sort="Hosseini, Mostafa" uniqKey="Hosseini M" first="Mostafa" last="Hosseini">Mostafa Hosseini</name><affiliation><nlm:aff id="aff5">Pediatric Chronic Kidney Disease Research Center, Tehran University of Medical Sciences, Tehran Iran.</nlm:aff><wicri:noCountry code="subfield">Tehran Iran.</wicri:noCountry></affiliation><affiliation wicri:level="1"><nlm:aff id="aff6">Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Iran</country><wicri:regionArea>Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran</wicri:regionArea><wicri:noRegion>Tehran</wicri:noRegion></affiliation></author><author><name sortKey="Safari, Saeed" sort="Safari, Saeed" uniqKey="Safari S" first="Saeed" last="Safari">Saeed Safari</name><affiliation wicri:level="1"><nlm:aff id="aff7">Proteomics Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Iran</country><wicri:regionArea>Proteomics Research Center, Shahid Beheshti University of Medical Sciences, Tehran</wicri:regionArea><wicri:noRegion>Tehran</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff8">Emergency Department, Shohadye Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Iran</country><wicri:regionArea>Emergency Department, Shohadye Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran</wicri:regionArea><wicri:noRegion>Tehran</wicri:noRegion></affiliation></author></analytic><series><title level="j">Archives of Academic Emergency Medicine</title><idno type="eISSN">2645-4904</idno><imprint><date when="2020">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Background:</title><p>The purpose of the current systematic review is to evaluate the efficacy of antiviral therapies in treatment of COVID-19. In addition, clinical trials on the efficacy of antiviral therapies in the management of Severe Acute Respiratory Syndrome coronavirus (SARS-Cov) or Middle East Respiratory Syndrome coronavirus (MERS-CoV) have also been reviewed, in order to identify potential treatment options for COVID-19.</p></sec><sec><title>Method:</title><p>An extensive search was performed in Medline, Embase, Scopus, Web of Science and CENTRAL databases until the end of March 15, 2020. Two independent researchers performed the screening, and finally the related studies were included.</p></sec><sec><title>Results:</title><p>Only one clinical trial on the efficacy of antiviral therapy in management of COVID-19 was found. The results depicted that adding Lopinavir-Ritonavir to the standard treatment regimen of patients with severe COVID-19 has no benefits. Moreover, 21 case-series and case-report studies reported the prescription of antiviral agents in COVID-19, none of which can be used to determine the efficacy of antiviral therapies in confronting COVID-19. In addition, no clinical trials were found to be performed on the efficacy of antiviral agents in the management of SARS-CoV and MERS-CoV.</p></sec><sec><title>Conclusion:</title><p>The current evidence impede researchers from proposing an appropriate antiviral therapy against COVID-19, making the current situation a serious concern for international organizations such as World Health Organization (WHO). In the time of the current pandemic and future epidemics, organizations such as WHO should pursue more proactive actions and plan well-designed clinical trials so that their results can be used in managing future epidemics.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Wu, Z" uniqKey="Wu Z">Z Wu</name></author><author><name sortKey="Mcgoogan, Jm" uniqKey="Mcgoogan J">JM McGoogan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Alavi Moghaddam, M" uniqKey="Alavi Moghaddam M">M Alavi-Moghaddam</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Luk, Hkh" uniqKey="Luk H">HKH Luk</name></author><author><name sortKey="Li, X" uniqKey="Li X">X Li</name></author><author><name sortKey="Fung, J" uniqKey="Fung J">J Fung</name></author><author><name sortKey="Lau, Skp" uniqKey="Lau S">SKP Lau</name></author><author><name sortKey="Woo, Pcy" uniqKey="Woo P">PCY Woo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chen, X" uniqKey="Chen X">X Chen</name></author><author><name sortKey="Chughtai, Aa" uniqKey="Chughtai A">AA Chughtai</name></author><author><name sortKey="Dyda, A" uniqKey="Dyda A">A Dyda</name></author><author><name sortKey="Macintyre, Cr" uniqKey="Macintyre C">CR MacIntyre</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Alavi Moghaddam, M" uniqKey="Alavi Moghaddam M">M Alavi-Moghaddam</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rismanbaf, A" uniqKey="Rismanbaf A">A Rismanbaf</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhang, J" uniqKey="Zhang J">J Zhang</name></author><author><name sortKey="Zhou, L" uniqKey="Zhou L">L Zhou</name></author><author><name sortKey="Yang, Y" uniqKey="Yang Y">Y Yang</name></author><author><name sortKey="Peng, W" uniqKey="Peng W">W Peng</name></author><author><name sortKey="Wang, W" uniqKey="Wang W">W Wang</name></author><author><name sortKey="Chen, X" uniqKey="Chen X">X Chen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhu, R F" uniqKey="Zhu R">R-f Zhu</name></author><author><name sortKey="Gao, R L" uniqKey="Gao R">R-l Gao</name></author><author><name sortKey="Robert, S H" uniqKey="Robert S">S-H Robert</name></author><author><name sortKey="Gao, J P" uniqKey="Gao J">J-p Gao</name></author><author><name sortKey="Yang, S G" uniqKey="Yang S">S-g Yang</name></author><author><name sortKey="Zhu, C" uniqKey="Zhu C">C Zhu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cao, B" uniqKey="Cao B">B Cao</name></author><author><name sortKey="Wang, Y" uniqKey="Wang Y">Y Wang</name></author><author><name sortKey="Wen, D" uniqKey="Wen D">D Wen</name></author><author><name sortKey="Liu, W" uniqKey="Liu W">W Liu</name></author><author><name sortKey="Wang, J" uniqKey="Wang J">J Wang</name></author><author><name sortKey="Fan, G" uniqKey="Fan G">G Fan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chen, N" uniqKey="Chen N">N Chen</name></author><author><name sortKey="Zhou, M" uniqKey="Zhou M">M Zhou</name></author><author><name sortKey="Dong, X" uniqKey="Dong X">X Dong</name></author><author><name sortKey="Qu, J" uniqKey="Qu J">J Qu</name></author><author><name sortKey="Gong, F" uniqKey="Gong F">F Gong</name></author><author><name sortKey="Han, Y" uniqKey="Han Y">Y Han</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chen, Q" uniqKey="Chen Q">Q Chen</name></author><author><name sortKey="Quan, B" uniqKey="Quan B">B Quan</name></author><author><name sortKey="Li, X" uniqKey="Li X">X Li</name></author><author><name sortKey="Gao, G" uniqKey="Gao G">G Gao</name></author><author><name sortKey="Zheng, W" uniqKey="Zheng W">W Zheng</name></author><author><name sortKey="Zhang, J" uniqKey="Zhang J">J Zhang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Guan, Wj" uniqKey="Guan W">WJ Guan</name></author><author><name sortKey="Ni, Zy" uniqKey="Ni Z">ZY Ni</name></author><author><name sortKey="Hu, Y" uniqKey="Hu Y">Y Hu</name></author><author><name sortKey="Liang, Wh" uniqKey="Liang W">WH Liang</name></author><author><name sortKey="Ou, Cq" uniqKey="Ou C">CQ Ou</name></author><author><name sortKey="He, Jx" uniqKey="He J">JX He</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Han, X" uniqKey="Han X">X Han</name></author><author><name sortKey="Fan, Y" uniqKey="Fan Y">Y Fan</name></author><author><name sortKey="Wan, Yl" uniqKey="Wan Y">YL Wan</name></author><author><name sortKey="Shi, H" uniqKey="Shi H">H Shi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hu, Z" uniqKey="Hu Z">Z Hu</name></author><author><name sortKey="Song, C" uniqKey="Song C">C Song</name></author><author><name sortKey="Xu, C" uniqKey="Xu C">C Xu</name></author><author><name sortKey="Jin, G" uniqKey="Jin G">G Jin</name></author><author><name sortKey="Chen, Y" uniqKey="Chen Y">Y Chen</name></author><author><name sortKey="Xu, X" uniqKey="Xu X">X Xu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Huang, C" uniqKey="Huang C">C Huang</name></author><author><name sortKey="Wang, Y" uniqKey="Wang Y">Y Wang</name></author><author><name sortKey="Li, X" uniqKey="Li X">X Li</name></author><author><name sortKey="Ren, L" uniqKey="Ren L">L Ren</name></author><author><name sortKey="Zhao, J" uniqKey="Zhao J">J Zhao</name></author><author><name sortKey="Hu, Y" uniqKey="Hu Y">Y Hu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, W" uniqKey="Li W">W Li</name></author><author><name sortKey="Cui, H" uniqKey="Cui H">H Cui</name></author><author><name sortKey="Li, K" uniqKey="Li K">K Li</name></author><author><name sortKey="Fang, Y" uniqKey="Fang Y">Y Fang</name></author><author><name sortKey="Li, S" uniqKey="Li S">S Li</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lim, J" uniqKey="Lim J">J Lim</name></author><author><name sortKey="Jeon, S" uniqKey="Jeon S">S Jeon</name></author><author><name sortKey="Shin, Hy" uniqKey="Shin H">HY Shin</name></author><author><name sortKey="Kim, Mj" uniqKey="Kim M">MJ Kim</name></author><author><name sortKey="Seong, Ym" uniqKey="Seong Y">YM Seong</name></author><author><name sortKey="Lee, Wj" uniqKey="Lee W">WJ Lee</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Liu, K" uniqKey="Liu K">K Liu</name></author><author><name sortKey="Fang, Yy" uniqKey="Fang Y">YY Fang</name></author><author><name sortKey="Deng, Y" uniqKey="Deng Y">Y Deng</name></author><author><name sortKey="Liu, W" uniqKey="Liu W">W Liu</name></author><author><name sortKey="Wang, Mf" uniqKey="Wang M">MF Wang</name></author><author><name sortKey="Ma, Jp" uniqKey="Ma J">JP Ma</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Liu, L" uniqKey="Liu L">L Liu</name></author><author><name sortKey="Jian Ya, G" uniqKey="Jian Ya G">G Jian-Ya</name></author><author><name sortKey="Wan Mei, H" uniqKey="Wan Mei H">H Wan-mei</name></author><author><name sortKey="Xian Xiangjian Ya, G" uniqKey="Xian Xiangjian Ya G">G Xian-xiangJian-ya</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Qin, X" uniqKey="Qin X">X Qin</name></author><author><name sortKey="Qiu, S" uniqKey="Qiu S">S Qiu</name></author><author><name sortKey="Yuan, Y" uniqKey="Yuan Y">Y Yuan</name></author><author><name sortKey="Zong, Y" uniqKey="Zong Y">Y Zong</name></author><author><name sortKey="Tuo, Z" uniqKey="Tuo Z">Z Tuo</name></author><author><name sortKey="Li, J" uniqKey="Li J">J Li</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shang, J" uniqKey="Shang J">J Shang</name></author><author><name sortKey="Du, R" uniqKey="Du R">R Du</name></author><author><name sortKey="Lu, Q" uniqKey="Lu Q">Q Lu</name></author><author><name sortKey="Wu, J" uniqKey="Wu J">J Wu</name></author><author><name sortKey="Xu, S" uniqKey="Xu S">S Xu</name></author><author><name sortKey="Ke, Z" uniqKey="Ke Z">Z Ke</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wang, D" uniqKey="Wang D">D Wang</name></author><author><name sortKey="Hu, B" uniqKey="Hu B">B Hu</name></author><author><name sortKey="Hu, C" uniqKey="Hu C">C Hu</name></author><author><name sortKey="Zhu, F" uniqKey="Zhu F">F Zhu</name></author><author><name sortKey="Liu, X" uniqKey="Liu X">X Liu</name></author><author><name sortKey="Zhang, J" uniqKey="Zhang J">J Zhang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wang, Z" uniqKey="Wang Z">Z Wang</name></author><author><name sortKey="Chen, X" uniqKey="Chen X">X Chen</name></author><author><name sortKey="Lu, Y" uniqKey="Lu Y">Y Lu</name></author><author><name sortKey="Chen, F" uniqKey="Chen F">F Chen</name></author><author><name sortKey="Zhang, W" uniqKey="Zhang W">W Zhang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wu, J" uniqKey="Wu J">J Wu</name></author><author><name sortKey="Liu, J" uniqKey="Liu J">J Liu</name></author><author><name sortKey="Zhao, X" uniqKey="Zhao X">X Zhao</name></author><author><name sortKey="Liu, C" uniqKey="Liu C">C Liu</name></author><author><name sortKey="Wang, W" uniqKey="Wang W">W Wang</name></author><author><name sortKey="Wang, D" uniqKey="Wang D">D Wang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Xu, Xw" uniqKey="Xu X">XW Xu</name></author><author><name sortKey="Wu, Xx" uniqKey="Wu X">XX Wu</name></author><author><name sortKey="Jiang, Xg" uniqKey="Jiang X">XG Jiang</name></author><author><name sortKey="Xu, Kj" uniqKey="Xu K">KJ Xu</name></author><author><name sortKey="Ying, Lj" uniqKey="Ying L">LJ Ying</name></author><author><name sortKey="Ma, Cl" uniqKey="Ma C">CL Ma</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yang, W" uniqKey="Yang W">W Yang</name></author><author><name sortKey="Cao, Q" uniqKey="Cao Q">Q Cao</name></author><author><name sortKey="Qin, L" uniqKey="Qin L">L Qin</name></author><author><name sortKey="Wang, X" uniqKey="Wang X">X Wang</name></author><author><name sortKey="Cheng, Z" uniqKey="Cheng Z">Z Cheng</name></author><author><name sortKey="Pan, A" uniqKey="Pan A">A Pan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Young, Be" uniqKey="Young B">BE Young</name></author><author><name sortKey="Ong, Swx" uniqKey="Ong S">SWX Ong</name></author><author><name sortKey="Kalimuddin, S" uniqKey="Kalimuddin S">S Kalimuddin</name></author><author><name sortKey="Low, Jg" uniqKey="Low J">JG Low</name></author><author><name sortKey="Tan, Sy" uniqKey="Tan S">SY Tan</name></author><author><name sortKey="Loh, J" uniqKey="Loh J">J Loh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhang, G" uniqKey="Zhang G">G Zhang</name></author><author><name sortKey="Hu, C" uniqKey="Hu C">C Hu</name></author><author><name sortKey="Luo, L" uniqKey="Luo L">L Luo</name></author><author><name sortKey="Fang, F" uniqKey="Fang F">F Fang</name></author><author><name sortKey="Chen, Y" uniqKey="Chen Y">Y Chen</name></author><author><name sortKey="Li, J" uniqKey="Li J">J Li</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhang, Z" uniqKey="Zhang Z">Z Zhang</name></author><author><name sortKey="Li, X" uniqKey="Li X">X Li</name></author><author><name sortKey="Zhang, W" uniqKey="Zhang W">W Zhang</name></author><author><name sortKey="Shi, Zl" uniqKey="Shi Z">ZL Shi</name></author><author><name sortKey="Zheng, Z" uniqKey="Zheng Z">Z Zheng</name></author><author><name sortKey="Wang, T" uniqKey="Wang T">T Wang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhou, Z" uniqKey="Zhou Z">Z Zhou</name></author><author><name sortKey="Xie, S" uniqKey="Xie S">S Xie</name></author><author><name sortKey="Zhang, J" uniqKey="Zhang J">J Zhang</name></author><author><name sortKey="Zheng, F" uniqKey="Zheng F">F Zheng</name></author><author><name sortKey="Jiang, D" uniqKey="Jiang D">D Jiang</name></author><author><name sortKey="Li, K" uniqKey="Li K">K Li</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Arabi, Ym" uniqKey="Arabi Y">YM Arabi</name></author><author><name sortKey="Asiri, Ay" uniqKey="Asiri A">AY Asiri</name></author><author><name sortKey="Assiri, Am" uniqKey="Assiri A">AM Assiri</name></author><author><name sortKey="Jokhdar, Haa" uniqKey="Jokhdar H">HAA Jokhdar</name></author><author><name sortKey="Alothman, A" uniqKey="Alothman A">A Alothman</name></author><author><name sortKey="Balkhy, Hh" uniqKey="Balkhy H">HH Balkhy</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Momattin, H" uniqKey="Momattin H">H Momattin</name></author><author><name sortKey="Al Ali, Ay" uniqKey="Al Ali A">AY Al-Ali</name></author><author><name sortKey="Al Tawfiq, Ja" uniqKey="Al Tawfiq J">JA Al-Tawfiq</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dawson, P" uniqKey="Dawson P">P Dawson</name></author><author><name sortKey="Malik, Mr" uniqKey="Malik M">MR Malik</name></author><author><name sortKey="Parvez, F" uniqKey="Parvez F">F Parvez</name></author><author><name sortKey="Morse, Ss" uniqKey="Morse S">SS Morse</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Morra, Me" uniqKey="Morra M">ME Morra</name></author><author><name sortKey="Van, Thanh L" uniqKey="Van T">Thanh L Van</name></author><author><name sortKey="Kamel, Mg" uniqKey="Kamel M">MG Kamel</name></author><author><name sortKey="Ghazy, Aa" uniqKey="Ghazy A">AA Ghazy</name></author><author><name sortKey="Altibi, Ama" uniqKey="Altibi A">AMA Altibi</name></author><author><name sortKey="Dat, Lm" uniqKey="Dat L">LM Dat</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gross, Ae" uniqKey="Gross A">AE Gross</name></author><author><name sortKey="Bryson, Ml" uniqKey="Bryson M">ML Bryson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Momattin, H" uniqKey="Momattin H">H Momattin</name></author><author><name sortKey="Mohammed, K" uniqKey="Mohammed K">K Mohammed</name></author><author><name sortKey="Zumla, A" uniqKey="Zumla A">A Zumla</name></author><author><name sortKey="Memish, Za" uniqKey="Memish Z">ZA Memish</name></author><author><name sortKey="Al Tawfiq, Ja" uniqKey="Al Tawfiq J">JA Al-Tawfiq</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stockman, Lj" uniqKey="Stockman L">LJ Stockman</name></author><author><name sortKey="Bellamy, R" uniqKey="Bellamy R">R Bellamy</name></author><author><name sortKey="Garner, P" uniqKey="Garner P">P Garner</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Iran</li><li>Iraq</li></country></list><tree><country name="Iran"><noRegion><name sortKey="Yousefifard, Mahmoud" sort="Yousefifard, Mahmoud" uniqKey="Yousefifard M" first="Mahmoud" last="Yousefifard">Mahmoud Yousefifard</name></noRegion><name sortKey="Hosseini, Mostafa" sort="Hosseini, Mostafa" uniqKey="Hosseini M" first="Mostafa" last="Hosseini">Mostafa Hosseini</name><name sortKey="Madani Neishaboori, Arian" sort="Madani Neishaboori, Arian" uniqKey="Madani Neishaboori A" first="Arian" last="Madani Neishaboori">Arian Madani Neishaboori</name><name sortKey="Safari, Saeed" sort="Safari, Saeed" uniqKey="Safari S" first="Saeed" last="Safari">Saeed Safari</name><name sortKey="Safari, Saeed" sort="Safari, Saeed" uniqKey="Safari S" first="Saeed" last="Safari">Saeed Safari</name><name sortKey="Zali, Alireza" sort="Zali, Alireza" uniqKey="Zali A" first="Alireza" last="Zali">Alireza Zali</name><name sortKey="Zarghi, Afshin" sort="Zarghi, Afshin" uniqKey="Zarghi A" first="Afshin" last="Zarghi">Afshin Zarghi</name></country><country name="Iraq"><noRegion><name sortKey="Mohamed Ali, Kosar" sort="Mohamed Ali, Kosar" uniqKey="Mohamed Ali K" first="Kosar" last="Mohamed Ali">Kosar Mohamed Ali</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/MersV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000294 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000294 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= MersV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= PMC:7156260
|texte= Antiviral therapy in management of COVID-19: a systematic review on current evidence
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:NONE" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a MersV1
| This area was generated with Dilib version V0.6.33. |  |